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      福瑞沃農大產品>>粉劑
     
    硫酸安普霉素可溶性粉
     
     
    獸藥GMP驗收通過企業

      批準文號:(2016)041122745

                           硫酸安普霉素可溶性粉

      【獸藥名稱】

      通用名稱:硫酸安普霉素可溶性粉

      商品名稱: 吉普欣

      英文名稱:Apramycin Sulfate Soluble Powder

      漢語拼音:Liusuan Anpumeisu Kerongxingfen

      【主要成分】  硫酸安普霉素

      【性狀】  本品為微黃色至黃褐色粉末。

      【藥理作用】  藥效學  安普霉素屬氨基糖苷類抗生素,對多種革蘭氏陰性菌(如大腸桿菌、假單胞菌、沙門氏菌、克雷伯氏菌、變形桿菌、巴氏桿菌、豬痢疾密螺旋體、支氣管炎敗血博代氏桿菌)及葡萄球菌和支原體均具殺菌活性。

      安普霉素獨特的化學結構可抗由多種質粒編碼鈍化酶的滅活作用,因而革蘭氏陰性菌對其較少耐藥,許多分離自動物的病原性大腸桿菌及沙門氏菌對其敏感。安普霉素與其他氨基糖苷類不存在染色體突變引起的交叉耐藥性。

      藥動學  內服可部分吸收(尤其新生仔畜),吸收量同劑量有關,并隨動物年齡增長而減少。藥物以原形通過腎臟排泄。犢消除半衰期為 4.4 小時,綿羊、兔和雞的消除半衰期為 0.8~1.7 小時。

      【藥物相互作用】  (1)與青霉素類或頭孢菌素類合用有協同作用。

      (2)本品在堿性環境中抗菌作用增強,與堿性藥物(如碳酸氫鈉、氨茶堿等)合用可增強抗菌效力,但毒性也相應增強。當 pH 超過 8.4 時,抗菌作用反而減弱。

      (3)與鐵銹接觸可使藥物失活。

      (4)與頭孢菌素、右旋糖酐、強效利尿藥(如呋塞米等)、紅霉素等合用,可增強本品的耳毒性。

      (5)骨骼肌松弛藥(如氯化琥珀膽堿等)或具有此種作用的藥物可加強本品的神經肌肉阻滯作用。

      【作用與用途】 氨基糖苷類抗生素。主要用于治療豬、雞革蘭氏陰性菌引起的腸道感染。

      【用法與用量】 以本品計。混飲:每 1L 水,雞 2.5~5g,連用 5 日;每 1kg 體重,豬 0.125 g,連用 7 日。

      【不良反應】  內服可能損害腸壁絨毛而影響腸道對脂肪、蛋白質、糖、鐵等的吸收。也可引起腸道菌群失調,發生厭氧菌或真菌等二重感染。

      【注意事項】  (1)蛋雞產蛋期禁用。

      (2)本品遇鐵銹易失效,混飼機械要注意防銹,也不宜與微量元素制劑混合使用。 (3)飲水給藥必須當天配制。

      【休藥期】  豬 21 日,雞 7 日。

      【規格】  100g:10g(1000 萬單位)

      【包裝】 100g/袋

      【貯藏】  避光,密閉,在干燥處保存。

      【有效期】 2年

      【生產企業】山西瑞象生物藥業有限公司

      地址:太原經濟技術開發區大昌南路15號(山西省團校北100米)

      郵編:030032

      銷售熱線:0351-5675157
     


    版權所有山西瑞象·福瑞沃農大生物公司 Copyright @2008 furuiwo Corp,LTD. 晉ICP備09000294號
    地址:山西省太原市小店區經濟技術開發區大昌南路15號。 郵編:030032 電話:15333644068 技術支持:龍騰偉業  
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